COMMENTS

  1. 20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine

    During the study period from 5 to 20 years, the absolute risk of distant recurrence among patients with T1N0 breast cancer was 10% for low-grade disease, 13% for moderate-grade disease, and 17% ...

  2. Metastatic recurrence in women diagnosed with non-metastatic breast

    Background To assess proportions of metastatic recurrence in women initially diagnosed with non-metastatic breast cancer by stage at diagnosis, breast cancer subtype, calendar period and age. Methods A systematic search of MEDLINE and Web of Science databases (January 2010-12 May 2022) was conducted. Studies reporting the proportion of distant metastatic recurrence in women with non ...

  3. A Systematic Review of Estimating Breast Cancer Recurrence at the

    Breast: Group Health Research Institute: ICD-9: 1892: 74.4: 1993-2006: All recurrences (local, regional, and distant) or second breast primary: Kroenke, 2016 : United States: ... studies using algorithms to identify breast cancer recurrence at the population level using administrative data were able to correctly identify recurrence with high ...

  4. The lingering mysteries of metastatic recurrence in breast cancer

    However, it is most often the result of relapse (recurrence), where metastases manifest after definitive treatment. 7 Metastatic recurrence is a significant problem in patients with breast cancer ...

  5. Reducing the Risk of Breast Cancer Recurrence: an Evaluation of the

    Abstract. With recent medical advances in diagnosis and treatment, the increasing numbers of long-term survivors of breast cancer is considerable and has resulted in the expansion of scientific research to include examination of lifestyle modifications as means of prevention of recurrence, new breast cancer events, and mortality.

  6. Risk of Recurrence in Patients With HER2+ Early-Stage Breast Cancer

    Breast cancer (BC) is a heterogeneous disease that can be classified by molecular subtype based on the genes that are expressed.1,2 One of these BC subtypes is driven by human epidermal growth factor receptor 2 (hereafter termed HER2+).1 Nearly 15% of all BCs and 15% to 20% of early-stage BCs (EBCs) overexpress HER2 or are amplified for the HER2 gene.3 Typically, HER2+ BCs are characterized as ...

  7. Pathways to Breast Cancer Recurrence

    Breast cancer recurrence is too complex a problem to be understood entirely through laboratory investigations or the clinical observations alone. ... et al. Loss of Dicer expression is associated with breast cancer progression and recurrence. Breast Cancer Research and Treatment. 2012;135:403-413. doi: 10.1007/s10549-012-2169-3. [Google ...

  8. Prevention of Late Recurrence: An Increasingly Important Target for

    Breast cancer recurrence has become an increasingly important aspect of cancer control as the number of breast cancer survivors continues to increase ().It was previously thought that the risk of recurrence decreases 5 years after diagnosis; however, an increasing body of literature has sustained a considerable risk of "late recurrence" beyond the canonical time frame (4,5).

  9. Collecting long-term outcomes in population-based cancer registry data

    Collecting long-term outcomes in population-based cancer registry data: the case of breast cancer recurrence. Researchers from the International Agency for Research on Cancer (IARC) and partner institutions reviewed studies that used population-based cancer registry data, to determine the current availability of data related to cancer recurrence in women initially diagnosed with non-metastatic ...

  10. How breast cancer recurrences are found

    Patients and methods . From a prospective cohort of 621 women diagnosed and treated for early invasive breast cancer between 2003 and 2013, we analysed the patients who were later diagnosed with distant metastases (n = 61) and the patients who had locoregional recurrences (LRR; n = 34).The patients had routine control visits for up to 10 years from initial diagnosis, with annual clinical ...