The National Institute on Aging Health Disparities Research Framework
Affiliations.
- 1 1.National Institute on Aging of the National Institute of Health.
- 2 2. Center for Aging in Diverse Communities at the Department of Medicine at the University of California, San Francisco.
- 3 3. American Psychological Association.
- PMID: 26675362
- PMCID: PMC4671408
- DOI: 10.18865/ed.25.3.245
Objective: Development of a new framework for the National Institute on Aging (NIA) to assess progress and opportunities toward stimulating and supporting rigorous research to address health disparities.
Design: Portfolio review of NIA's health disparities research portfolio to evaluate NIA's progress in addressing priority health disparities areas.
Results: The NIA Health Disparities Research Framework highlights important factors for health disparities research related to aging, provides an organizing structure for tracking progress, stimulates opportunities to better delineate causal pathways and broadens the scope for malleable targets for intervention, aiding in our efforts to address health disparities in the aging population.
Conclusions: The promise of health disparities research depends largely on scientific rigor that builds on past findings and aggressively pursues new approaches. The NIA Health Disparities Framework provides a landscape for stimulating interdisciplinary approaches, evaluating research productivity and identifying opportunities for innovative health disparities research related to aging.
Keywords: Aging; Health Disparities.
Publication types
- Research Support, N.I.H., Extramural
- Health Services Research / methods*
- Health Services for the Aged*
- Healthcare Disparities*
- National Institute on Aging (U.S.) / statistics & numerical data*
- United States
Grants and funding
- P30 AG015272/AG/NIA NIH HHS/United States
- R25 GM058641/GM/NIGMS NIH HHS/United States
- P30 AG15272/AG/NIA NIH HHS/United States
COMMENTS
The NIA Health Disparities Research Framework showcases priorities and investments in this important aging research area. This page is designed to serve as a resource for scientists interested in investigating health disparities related to aging. The Framework outlines four key levels of analysis related to disparities research-environmental ...
NIA Health Disparities Research Framework: The framework is overseen by the Office of Special Populations (OSP) and outlines four key levels of analysis related to disparities research — environmental, sociocultural, behavioral, and biological — with priority focus areas in each category. Using the framework as a guide, NIA has awarded more ...
The NIA-AA research framework proposes three general groups of biomarkers—beta-amyloid, tau and neurodegeneration or neuronal injury—and leaves room for other and future biomarkers. Beta-amyloid is a naturally occurring protein that clumps to form plaques in the brain. Tau, another protein, accumulates abnormally forming neurofibrillary ...
2018 National Institute on Aging—Alzheimer's Association (NIA-AA) Research Framework NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease Clifford R. Jack, Jr.,a,*, David A. Bennettb, Kaj Blennowc, Maria C. Carrillod, Billy Dunne, Samantha Budd Haeberleinf, David M. Holtzmang, William Jagusth, Frank Jesseni,
the NIA-AA to update22 and unify the 2011 guidelines. This unifying update is labeled a "research 23 framework", because its intended use is for observational and interventional research, not routine 24 clinical care. In the NIA AA research framework Alzheimer's disease (AD) is defined by its
In the National Institute on Aging and Alzheimer's Association Research Framework, Alzheimer's disease (AD) is defined by its underlying pathologic processes that can be documented by postmortem ...
diseases other than AD. This research framework does not ignore these individuals but rather provides a system for characterizing them alongside individuals who are in the Alzheimer's continuum. 2. Background: Rationale for updating 2011 NIA-AA guidelines for AD In 2011, the National Institute on Aging and Alzheimer's Association (NIA-AA ...
Objective: Development of a new framework for the National Institute on Aging (NIA) to assess progress and opportunities toward stimulating and supporting rigorous research to address health disparities. Design: Portfolio review of NIA's health disparities research portfolio to evaluate NIA's progress in addressing priority health disparities areas.
The NIA Health Disparities Framework provides a landscape for stimulating interdisciplinary approaches, evaluating research productivity and identifying opportunities for innovative health ...
The NIA-AA Research Framework [1] represents important progress. This approach will be useful in designing clinical trials and has an important role in characterizing the biomarker profile of participants entering trials. The Framework will assist in excluding Alzheimer spectrum participants from trials of non-Alzheimer dementias.