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- Published: 08 May 2024
Autoimmune diseases
BiTE therapy for rheumatoid arthritis
- Frances Humby ORCID: orcid.org/0000-0003-1280-9133 1 ,
- Bruce Kirkham 1 &
- Leonie Taams ORCID: orcid.org/0000-0002-9337-7194 2
Nature Medicine volume 30 , pages 1533–1534 ( 2024 ) Cite this article
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A pilot study suggests that the bispecific T cell engager blinatumomab may provide a new therapy for patients with refractory rheumatoid arthritis; larger studies and deep phenotyping will be crucial to thoroughly evaluate and optimize this approach.
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Department of Rheumatology, Guy’s Hospital, Great Maze Pond, London, UK
Frances Humby & Bruce Kirkham
Centre for Inflammation Biology & Cancer Immunology, Department of Inflammation Biology, School of Immunology and Microbial Science, King’s College London, London, UK
Leonie Taams
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Correspondence to Frances Humby .
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Competing interests.
L.T. reports consultant or speaker fees from GSK and AbbVie; and research funding from Sanofi. B.K. reports consultant or speaker fees from Abbvie, Eli Lilly, Galapagos, Janssen, Novartis, Pfizer and UCB. F.H. reports consultant or speaker fees from Galapagos, Roche and Abbvie.
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Humby, F., Kirkham, B. & Taams, L. BiTE therapy for rheumatoid arthritis. Nat Med 30 , 1533–1534 (2024). https://doi.org/10.1038/s41591-024-02982-z
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Published : 08 May 2024
Issue Date : June 2024
DOI : https://doi.org/10.1038/s41591-024-02982-z
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